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KMID : 0369319920120010070
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Allergy
1992 Volume.12 No. 1 p.70 ~ p.77
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Etiologic Allergens, Blood Eosinophil Count and Total IgE Level according to Age and Site of Skin Lesion in Atopic Dermatitis
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Abstract
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A clinical study was done on 61 cases of atopic dermatitis who visited the pediatric allergy clinic in Soon Chun Hyang University Hospital from June 1987 to June 1991.
We reviewed their clinical history, blood eosinophil count, serum IgE level by PRIST, specific IgE antibody by RAST and skin prick test comparing age and site of skin lesions.
@ES The results were summerized as follows:
@EN 1) Male to female ration was 1.18:1 and peak incidence was between one and three years of age (39.3%).
2) Blood eosinophil count increased in study subjects but there was no significant correlation between eosinophil count and age and site of skin lesion.
3) Total serum IgE levels increased with age and we can find higher IgE level in patient with skin lesions distributed over whole body.
4) By RAST and skin prick test, most popular etiologic allergens in patients under 1 year of age were foods (egg, milk). Whereas inhalant allergens (house dust mite) became more important with age.
5) Inhalant allergens (house bust mite) were predominant in patients with skin lesions distributed over whole body or exposed area such as face.
6) Incidence of atopic dermatitis was higher in patients with allergic family history, past history of infantile eczema and artificial milk feeding.
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